Skeeter Syndrome Treatment

As with most allergies, Skeeter Syndrome treatment deals primarily with prevention, and symptom management. That is, treating the individual symptoms as they appear or attempting to preempt them with the help of medications. It’s a good idea to have a medical kit at home to help manage symptoms that might appear.

This includes oral antihistamines, anti-itch creams,  anti-inflammatory and pain medication.  Treatment usually involves treating swelling, itching, and discomfort both topically and internally.

Important: Individuals who have suffered a serious allergic reaction, such as anaphylaxis, to other insect bites should have an  epinephrine autoinjector (EpiPen) on hand at all times as anaphylaxis can occur with mosquito allergies.

The itching associated with a  regular mosquito bite tends to be magnified a lot with skeeter syndrome. Added to the swelling, blistering and possibility of infection it can be the most torturous symptom. Alleviating the symptoms is key to avoiding the bite becoming infected or developing into blisters or a raw sore. 

Thankfully, there are many medications, both natural and secular to help alleviate this uncomfortable sensation.

Skeeter Syndrome Treatment – Anti-Itch Treatments

Topical Benadryl

Skeeter Syndrome Treatment - Benadryl Topical Itch Stopping Cream, Extra Strength, 1-Ounce Tubes (Pack of 4) Topical Benadryl is an important item and should be kept on hand at all times. There are different strengths, but the extra strength is the best choice due to the severity of the symptoms. The ointment is applied directly to the affected area as often as needed.

Calamine Lotion

Skeeter Syndrome Treatment - Caladryl Lotion, Calamine Plus Itch Reliever, 6-Ounce Bottle Calamine lotion is one of the most effective topical solutions to relieve itching. It contains a mixture of Zinc Oxide and Ferric Oxide, and is commonly used to treat poison oak, poison ivy and poison sumac. It also helps dry weeping or oozing caused by irritation.


Calamine lotion is for external use only, and you should avoid getting it in your eyes, nose, mouth or genital/anal areas. There are no known drug interactions, but be sure to let your pharmacist know if you have other drug allergies or are on other medications.

Baking soda

Skeeter Syndrome Treatment - ARM & HAMMER Baking Soda - 13.5 lb. bag

Baking soda is a natural option for topical treatment of itching and discomfort. Mix a little water with baking soda and apply the paste to the affected area to relieve itching.

Add baking soda to a hot bath, and take a long soak. It will help with swelling, redness and itching as well as help you avoid infections.

Apple Cider Vinegar

Skeeter Syndrome Treatment - Bragg Apple Cider Vinegar Organic Raw -- 32 fl oz


Apple cider vinegar also has natural anti-itch benefits. Wet a cotton ball with vinegar and use a band aid or medical tape to apply it to the affected area for extended relief.

Hydrocortisone Cream

Skeeter Syndrome Treatment - Cortizone-10 Max Strength Cortizone-10 Crme, 2oz Boxes (Pack of 2)  Hydrocortisone cream is a topical treatment that is commonly used to treat eczema. It helps with swelling, redness, itching and discomfort.  It works wonders for extremely inflamed bites, and as a preemptive treatment.


In many cases bites don’t turn into welts for a few days, so treating the bite before it swells is a good idea to avoid and minimize discomfort.

Hydrocortisone is a topical steroid, so be sure to consult your physician if you are on prescription medication or suffer from a medical condition.

 Skeeter Syndrome Treatments for Inflammation


Skeeter syndrome Treatment - Genuine Bayer Aspirin 325mg Tablets 200 Coated Tablets


A well-kept secret is that aspirin works well as a topical pain reliever & anti-inflammatory. Crush a few pills and add a few drops of water. Apply the paste to the affected area, leave it on overnight for maximum effect. 


Benadryl or Sudafed

Skeeter Syndrome treatment - Benadryl® Allergy Ultratabs - 148 tabletsBenadryl, Sudafed any other oral antihistamines can help you treat & manage Skeeter Syndrome Symptoms. Take a dose at can  help treat swelling, and relieve itching for hours.

This is especially useful important if you have a bite in an awkward place, such as your but or toes,  and can help you avoid embarrassing situations.



Meat Tenderizer

Skeeter Syndrome Treatment - Badia, Meat Tenderizer, 4.5-OunceYes, believe it or not meat tenderizer that contains papain is helpful in treating Skeeter Syndrome. Papain is an enzyme that helps breaks down the proteins found in the mosquito saliva. This can be especially helpful in relieving skeeter syndrome symptoms, and preempting a serious outbreak.



7 thoughts on “Skeeter Syndrome Treatment

  1. Ella Crutz

    I really enjoy examining on this web site , it has got good blog posts. “For Brutus is an honourable man So are they all, all honourable men.” by William Shakespeare.

  2. Pingback: FAQ about Skeeter Syndrome & Mosquito Bite Allergies - Skeeter Syndrome

  3. Vera

    Meat tenderizer is THE BEST for itch relief, and it works FAST (takes only a few seconds to feel the difference!). The easiest way to do it: take a small amount of powder, add a few drops of water to make a paste, spread on itchy spots.

    Our regimen: when itching begins, apply meat tenderizer for a few minutes, wipe off, then apply Hydrocortisone cream (this combination provides about 6 hours of itch relief). Plus, give a dose of Benadryl every 6 hours.

  4. Charlotte Shirvington

    I have started to have severe reactions to mosquito bites the past 3 years. It all started after I was bitten by a horsefly. Before then, I had little to no reaction to the things. Now, I get a red lump, the tlast time (2 months ago) I had a yellow patch in the middle of all the read. The next day it started to blister up, and it was the worst blister I have had. The redness spread out in a huge circle on my leg, and at the biggest it almost touched from one side of my leg round to the other. It was so painful. I had to get to the emergency room asap for them to look at it and give me some hardcore antibiotics. That sucked so bad. I only had one bad bite last year and the year before, so I don’t know what I’m doing to make me react once? No idea. I’m hoping for no more this year. Funny thing is, it’s only when they bite the fleshy part of ym lower leg. I got 2 mossy bites on my inner thigh, above the knee- no reaction. I got a bite the other day just below my ankle- no reaction. It is insane why it reacts there.

  5. Chasity Carpenter

    My 12 yr old son has 6 huge circles on his legs and 1 on his arm it was Skeeter bites but it had swelled made blisters which popped so it was all raw skin. The doctor said ringworm at first but then said Skeeter bites , we knew he was allergic but it never did this. It’s been bout a month the places is healing but really dry is there anything to help that?


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